The primary goal of my lecture session is to provide an open and friendly environment where students can feel comfortable expressing their questions without feeling that their questions might be simple or off-topic. While each session is composed of students with different personalities, my teaching approach is individualized so that my students are motivated to challenge themselves, make mistakes and learn from those mistakes. Through this approach, I want to make sure that the discussed topic is clear to every student and no student is left behind. A key point of my teaching philosophy is the development of critical-thinking skills. While teaching is a lifelong learning experience, I will continue my pursuit for knowledge so that I become a better teacher and mentor.
Our research seeks structural and functional insights into novel proteins and protein complexes, and how their assembly and/or activation is involved in pathophysiology of human cancers. More specifically, our research interests focus on i) understanding the structure-function relationships of novel immunomodulatory proteins in cancer, and ii) developing novel approaches for targeting difficult proteins that are involved in cancer progression. Ultimate goal is to develop target-specific small molecule modulators that can be used either for therapeutic purposes or as agents to understand the biological function of the protein under study.
To accomplish these goals, we follow a multidisciplinary approach in the interface of chemistry and biology that includes but is not limited to protein expression, purification and characterization, protein X-ray crystallography, protein dynamics, protein engineering, small molecule high-throughput screening, an array of in vitro biochemical and biophysical assays, in vivo assays and computational chemistry.